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产品目录

重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)图片
产品货号:
JN0768
中文名称:
重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)
英文名称:
Recombinant Human Membrane Primary Amine Oxidase
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Arg27-Asn763在C端含有His标签。

VAP-1/AOC3质量控制:>95%(还原性SDS-PAGE)

VAP-1/AOC3制剂:液体

VAP-1/AOC3保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于VAP-1/AOC3
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inflammation through its release from intracellular granules in which the protein is stored. The adhesive function of VAP-1 has been demonstrated in studies showing that the protein is important for the adherence of certain lymphocyte subtypes to inflamed endothelial tissues. VAP-1 mediated adhesion is involved in the process of leukocyte extravasation, an important feature of inflammatory responses. VAP-1 is considered to be a therapeutic target for diabetes, oxidative stress, and inflammatory diseases.
相关搜索:重组人VAP-1(血管黏附蛋白1)(膜伯胺氧化酶)Recombinant Human Membrane Primary Amine Oxidase
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